Climate effect of inhaled anaesthetics

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Climate effect of inhaled anaesthetics.

Almost all areas of human activity have the potential to influence climate. The administration of inhalation anaesthetics is one such activity. However, since the first dedicated study in 1989 of the possible role of halogenated anaesthetics, they have received only sporadic interest. Two recent papers, published in this issue of the British Journal of Anaesthesia and in Anesthesia and Analgesi...

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Inhaled anaesthetics have no effect on fertility in Drosophila melanogaster.

The potential effects of enflurane, isoflurane, halothane, fluroxene and nitrous oxide on mortality and fertility in Drosophila melanogaster were examined. The LD50 value 1 day after exposure for 1 h was the same for males and females and was about 8% for enflurane, isoflurane and halothane, about 20% for fluroxene, and greater than 100% for nitrous oxide. Male and female fertility, however, we...

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Sodium channels and the synaptic mechanisms of inhaled anaesthetics.

General anaesthetics act in an agent-specific manner on synaptic transmission in the central nervous system by enhancing inhibitory transmission and reducing excitatory transmission. The synaptic mechanisms of general anaesthetics involve both presynaptic effects on transmitter release and postsynaptic effects on receptor function. The halogenated volatile anaesthetics inhibit neuronal voltage-...

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Separation of cough and reflex bronchoconstriction by inhaled local anaesthetics.

Cough and airway constriction are common features of respiratory diseases. Both can be caused by stimulation of airway nerves. We have studied the effects of airway anaesthesia on these reflexes, stimulated by inhaled capsaicin, in order to determine whether they are controlled by the same sensory nerves. Ten volunteers had capsaicin cough dose responses performed before and at 10 min after inh...

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Measurement and reduction of occupational exposure to inhaled anaesthetics.

The occupational exposure of hospital staff to inhaled anaesthetics was investigated using a personal sampling device that provides a measure of the average concentrations breathed by a person over a period of time, as distinct from the spot sampling in the general environment. The anaesthetist's average exposure to nitrous oxide and halothane during complete operating sessions was twice that e...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 2010

ISSN: 0007-0912

DOI: 10.1093/bja/aeq313